Ethyl 2-(4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinolin-3-yl)acetate
نویسندگان
چکیده
منابع مشابه
(Z)-Ethyl 2-oxo-3-(1,2-dihydroquinolin-2-ylidene)propanoate
Both independent mol-ecules in the asymmetric unit of the tautomeric title compound, C(14)H(13)NO(3), a synthetic product obtained from 2-lithio-methyl-quinoline and diethyl oxalate, crystallize in the enaminone form with a Z configuration around the double bond. Intra-molecular N-H⋯O hydrogen bonds occur, generating an S(6) graph-set motif. In the crystal, weak inter-molecular C-H⋯O and π-π st...
متن کاملEthyl 6-methyl-3-(2-methylprop-1-enyl)-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate
In the mol-ecule of the title compound, C(18)H(22)N(2)O(3), the dihydro-pyrimidinone ring adopts an envelope conformation. The dihedral angle between the phenyl ring and the mean plane through the enamine fragment is 86.04 (7)°. The mol-ecular conformation is stabilized by an intra-molecular C-H⋯O hydrogen bond. In the crystal, inter-molecular N-H⋯O hydrogen bonds link pairs of mol-ecules into ...
متن کاملEthyl 2-(4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinolin-3-yl)acetate
In the title compound, C(14)H(15)NO(4), the bicyclic fragment and the ester group form a dihedral angle of 86.7 (2)°. Inter-molecular O-H⋯O and C-H⋯O hydrogen bonding connects mol-ecules into a helix along the crystallographic b axis.
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The title compound, C(26)H(24)FNO(3), is a critical inter-mediate of a selective and competitive inhibitor of the enzyme 3-hy-droxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase. Inter-molecular N-H⋯O hydrogen bonding generates a chain along [give direction] that is the dominant inter-action in the crystal packing. Inter-molecular C-H⋯O inter-actions are also observed.
متن کاملEthyl 3′-cyano-1′-methyl-2-oxo-4′-phenylspiro[acenaphthene-1,2′-pyrrolidine]-3′-carboxylate
In the title compound, C(26)H(22)N(2)O(3), the acenaphthen-1-one ring system is nearly planar and the pyrrolidine ring adopts a distorted envelope conformation. An inter-molecular C-H⋯O hydrogen bond stabilizes the crystal structure.
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2009
ISSN: 1600-5368
DOI: 10.1107/s1600536809011921